Monday, 19 November 2018
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Dr. M. V. Joseph




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Immunotechnology Laboratory

The major focus of the laboratory is on identification, isolation and characterization of bioactive molecules having immunomodulatory and in vitro cytotoxic activity against cancers (mouse and human). In vivo antitumour studies are carried out employing mouse models. In silico screening of compounds and docking studies are also being pursued actively. Other lab interests include immunological aspects related to Helicobacter pylori as well as monoclonal antibody production for therapeutic applications.

List of Publications

Rahul Raghavan, Sanith Cheriyamundath, and Joseph Madassery (2012). Andrographolide, a new potential NF-кB inhibitor: docking simulation and evaluation of drug-likeness. Molecular simulation,. Vol.38(7) 2012. DOI.10.1080/08927022.2011.651138

Rekha. T. Kootackal Poulose Martin, Sreekumar. V.B. and Joseph Madassery (2011). Genetic diversity assessment of rarely cultivated traditional Indica rice (Oryza sativa) Biotechnology Research international Vol.2011 article ID 784719.Doi.10.4061/2011/784719

Suneesh kumar pachthundikundi, Sabine brandt, Joseph Madassery, Steffen Backert. (2011) Induction of TLR-2 and TLR-5 expression by Helicobacter pylori switches cagPAI- dependent signaling leading to the secretion of IL-8 and TNF-α Vol.6 PLoS ONE 19614, 1-11

Awadesh kumar Arya, Kottacka Poulose Martin, Aneta Sabovljevic, Joseph Madassery ( 2011) Transformation through agroinfection on decapitated shoot apex of field- growing Phylanthus amarus, DOI 10.1007/s 11738-0110716-x

Kottackal Poulose Martin, A.K.Pradeep, Joseph madassery ( 2010) High frequency invitro propagation of Trichopus zelanicus subsp. Travancoricus using branch-petiole explants DOI 10.1007/s11738-010-0642-3

Martin K P, Zhang C L, Manoj E H, Slater A and Joseph Madassery (2008 ) Adventitious root induction in Ophiorrhiza prostrate : a tool for the production of camptothecin ( an anticancer drug ) and rapid propagation. Plant Biotechnol Rep. 2:163-169

Martin K.P. and Joseph Madassery ( 2007) Trichopus zeylanius subsp. travancorius ribosomal protein L16 (rpl16) mRNA, chloplast gi 155965995 gbEU057718.1 ( 1555965995 ), Gene Bank EU057718

Martin K.P. Gupta .S. Ahang CL, Slater A and Joseph Madassery (2007) Ophiorrhiza prostrate tryptophan decarboxylase ( tdc) gene gi155965995 gb EU057719.1 ( 155965997), Gene bank EU057719

Martin K P and Joseph Madassery ( 2007) Ophiorrhiza prostrate strain albino tryptophan decarboxylase (tdc) gene gi155965999 gb EU 057720.1(155965999) gene Bank EU057720

Martin K P, Zhang C L Slater A and Joseph Madassery (2007) Control of shoot necrosis and plant death during micro propagation of banana and plantain (Musa spp. ) Plant Cell Tiss Organ Cult 88:51-59

Manoj Emanuel Hembrom, Martin K P, Suneesh Kumar Pachathundikandi and Joseph Madassery. (2006) Rapid in vitro production of true-to-type plants of Pogostemon heyneanus through dedifferentiated axillary buds. In Vitro Cellular and Developmental Biology Plant DOI 10:1079

Martin K P and Joseph Madassery (2006) Rapid in vitro propagation of Dendrobium hybrids through direct shoot formation from foliar explants, and protocorm-like bodies. Scientia Horticulturae 108( 2006) 95-99

Last Updated ( Tuesday, 26 November 2013 )