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Dr. Smitha. V. B

Assistant Professor

            
 
 Addres office : Dept of Biotechnology, University of Calicut.
Address Residence : Pournami, Chithra Garden
Pangappara P. O, Trivandrum Pin 615581
Phone office :0494-2407403
Mobile : 9895456229
Email : This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
 
 
 
Qualifications          MSc. (Biotechnology), Ph.D) (Biotechnology)
Specialisation         Molecular Oncology
Publications
  1. Radhakrishnan E K, Smitha V B, Sai Shyam N, Lekshmi R N, Arun Kumar T, Soniya E V and Ruby J A, (2015). [6]-Gingerol induces caspase-dependent apoptosis and prevents PMA-induced proliferation in colon cancer cells by inhibiting MAPK/AP-1 signaling. 9(8), Impact factor-3.53 http://dx.plos.org/10.1371/journal. pone.0104401
  2. Chanickal N Sreekanth, Smitha V Bava, E Sreekumar and Ruby John Anto. (2011) Molecular evidences for the chemosensitizing efficacy of liposomal curcumin in paclitaxel chemotherapy in mouse models of cervical cancer. Oncogene. 30, 3139-3152.
  3. Smitha V Bava, Chanickal N Sreekanth, Arun Kumar T Thulasidasan, Nikhil P Anto, Vino T Cheriyan, Vineshkumar T Puliyappadamba, Sajna G Menon, Santhosh D Ravichandran, and Ruby John Anto. (2011) Akt is upstream and MAPKs are downstream of NF-κB in paclitaxel-induced survival signaling events, which are down-regulated by curcumin contributing to their synergism. Int J Biochem Cell Biol. 43, 331-341,
  4. Vineshkumar T Puliyappadamba, Vino T Cheriyan, Arun Kumar T Thulasidasan, Smitha V Bava, Balachandran S Vinod,Priya R Prabhu, Ranji Varghese, Arathy Bevin, Shalini Venugopal and Ruby John Anto. (2010) Nicotine-induced survival signaling in lung cancer cells is dependent on their p53 status while its down-regulation by curcumin is independent. Mol Cancer, 9, 220.
  5. Krishna P Laladhas, Vino T Cheriyan, Vineshkumar T Puliappadamba, Smitha V Bava, Rajesh G Unnithan, Parvathy L Vijayammal and Ruby John Anto. (2010) A novel protein fraction from Sesbania grandiflora induces apoptosis in cancer cells and shows potential anticancer and chemopreventive efficacy in vivo. J Cellular and Mol. Med. 14, 636-646,
  6. Sreekanth C N, Smitha V B, E Sreekumar and R J A, (2011). Molecular evidences for the chemosensitizing efficacy of liposomal curcumin in paclitaxel chemotherapy in mouse models of cervical cancer. Oncogene 30, 3139-3152, Impact factor 7.135. http://link.springer.com/chapter/10.1007/978-81-322-1533-2_3#page-1 Sreekanth C N, Smitha V B, E Sreekumar and R J A, (2011). Molecular evidences for the chemosensitizing efficacy of liposomal curcumin in paclitaxel chemotherapy in mouse models of cervical cancer. Oncogene 30, 3139-3152, Impact factor 7.135. http://link.springer.com/chapter/10.1007/978-81-322- 1533-2_3#page-1
  7. Smitha V B, Sreekanth C N, Arun Kumar T T, Nikhil P. A, Vino T C, Vineshkumar T P, Sajna G M, Santhosh D. R, Ruby John Anto ,( 2011). Akt is upstream and MAPKs are downstream of NF-κB in paclitaxel-induced survival signaling events, which are down-regulated by curcumin contributing to their synergism. The International Journal of Biochemistry & Cell Biology 43(3): 331-341 Impact factor 4.887. (http://www. sciencedirect.com/science/article/pii/ S1357272510003304
  8. Vineshkumar TP, Vino TC,, Arun KT,, Smitha V B, Vinod BS, Prabhu PR, Varghese R, Bevin A, Venugopal S, Anto RJ,(2010). Nicotine-induced survival signaling in lung cancer cells is dependent on their p53 status while its down-regulation by curcumin is independent. Molecular Cancer, 20 Impact factor 4.16. doi:10.1186/1476-4598-9-220. http://www.molecularcancer. com/content/9/1/220
  9. Laladhas KP.;, Vino TC, Vineshkumar TP, , Smitha VB, , Rajesh G U Vijayammal PL, Ruby J A,2010. A novel protein fraction from Sesbania grandiflora shows potential anticancer and chemopreventive efficacy, in vitro and in vivo. Journal of Cellular and Molecular Medicine 14 ( 3),363. Impact factor 5.228. http://onlinelibrary.wiley.com/doi/10.1111/j.1582-4934.2008.00648.x/full
  10. Smitha V B, Vineshkumar T P, Ayswaria D, Asha N, Karunagaran D, and Ruby J A, 2005. Sensitization of taxol-induced apoptosis by curcumin involves down regulation of NF-B and Akt and is independent of tubulin polymerization. J. Biol. Chem.,280: 6301 - 6308. Impact Factor 5.854 http://www.jbc.org/content/280/8/6301.short
Conference/ Symposia papers
  1. Chanickal. N. Sreekanth, Smitha. V. Bava and Ruby John Anto, Curcumin: A potent candidate to be evaluated as a chemosensitizer in paclitaxel chemotherapy against cervical cancer. Invited Talk, Fourth International Conference on Translational Cancer Research: Recent Developments in Cancer Prevention, Udaipur, Rajasthan, India, December 16th-19th, 2011
  2. Chanickal. N. Sreekanth, Smitha. V. Bava and Ruby John Anto, Chemosensitizing efficacy of curcumin in paclitaxel chemotherapy as evidenced by chemical-induced and xenograft models of cervical cancer, Session Talk, 3rd International Conference on Drug Discovery & Therapy-Feb 7 - 10, 2011, Dubai.
Books Chapters/Articles
  • Perspectives in Cancer Prevention-Translational Cancer Research. PR Sudhakaran, OV Oommen, MR Pillai - 2014 - Springer
 
 
 
 
Last Updated ( Wednesday, 27 January 2016 )